C16orf74 · rs147305137
Where this position leads
Condition: Celiac Disease
What the study found
Who was studied 394,642 European ancestry individuals.
The effect Each copy of the G allele shifted the measure 0.108 higher (95% confidence interval 0.08-0.136); p = 4 × 10−15.
How common The G allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 16, band 16q24.1 — in an intron of C16orf74.
rs147305137 is a single position in the genome, in or near the C16orf74 gene. Published research associates it with monocyte percentage (ukb data field 30190). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Monocyte percentage (UKB data field 30190) (rs147305137). MyGeneLog™. https://www.mygenelog.com/variants/rs147305137