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HDL cholesterol levels

GRID1 · rs147116709

What the study found

Who was studied 3,567 European ancestry men, 4,171 European ancestry women.

The effect Each copy of the A allele shifted the measure 0.47 higher (95% confidence interval 0.31-0.63); p = 5 × 10−10.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 10, band 10q23.1 — in an intron of GRID1.

What each result means

A/A Two copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs147116709

What is rs147116709?

rs147116709 is a single position in the genome, in or near the GRID1 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs147116709 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs147116709 come from?

GWAS Catalog, Atherosclerosis 2020, PMID:32109663. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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HDL cholesterol levels (rs147116709). MyGeneLog™. https://www.mygenelog.com/variants/rs147116709

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