Standard
Apolipoprotein B levels
CCDC93 · rs146962013
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0492 higher (95% confidence interval 0.034-0.064); p = 3 × 10−10.
How common The A allele had a frequency of about 92% in the people studied.
Where it sits Chromosome 2, band 2q14.1 — in an intron of CCDC93.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Apolipoprotein B levels compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Apolipoprotein B levels.
G/G
Published research associates this genotype with typical/baseline likelihood of Apolipoprotein B levels — no copies of the reported risk allele.
Source
Genome-wide characterization of circulating metabolic biomarkers
Karjalainen MK,
Karthikeyan S,
Oliver-Williams C,
Sliz E,
Allara E,
Fung WT,
Surendran P,
Zhang W,
Jousilahti P,
Kristiansson K,
Salomaa V,
Goodwin M
and 75 more — show all
Hughes DA,
Boehnke M,
Fernandes Silva L,
Yin X,
Mahajan A,
Neville MJ,
van Zuydam NR,
de Mutsert R,
Li-Gao R,
Mook-Kanamori DO,
Demirkan A,
Liu J,
Noordam R,
Trompet S,
Chen Z,
Kartsonaki C,
Li L,
Lin K,
Hagenbeek FA,
Hottenga JJ,
Pool R,
Ikram MA,
van Meurs J,
Haller T,
Milaneschi Y,
Kähönen M,
Mishra PP,
Joshi PK,
Macdonald-Dunlop E,
Mangino M,
Zierer J,
Acar IE,
Hoyng CB,
Lechanteur YTE,
Franke L,
Kurilshikov A,
Zhernakova A,
Beekman M,
van den Akker EB,
Kolcic I,
Polasek O,
Rudan I,
Gieger C,
Waldenberger M,
Asselbergs FW,
Hayward C,
Fu J,
den Hollander AI,
Menni C,
Spector TD,
Wilson JF,
Lehtimäki T,
Raitakari OT,
Penninx BWJH,
Esko T,
Walters RG,
Jukema JW,
Sattar N,
Ghanbari M,
Willems van Dijk K,
Karpe F,
McCarthy MI,
Laakso M,
Järvelin MR,
Timpson NJ,
Perola M,
Kooner JS,
Chambers JC,
van Duijn C,
Slagboom PE,
Boomsma DI,
Danesh J,
Ala-Korpela M,
Butterworth AS,
Kettunen J
Nature · 2024 · PMID 38448586 · open access
Questions about rs146962013
What is rs146962013?
rs146962013 is a single position in the genome, in or near the CCDC93 gene. Published research associates it with apolipoprotein b levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs146962013 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs146962013 come from?
GWAS Catalog, Nature 2024, PMID:38448586. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Apolipoprotein B levels (rs146962013). MyGeneLog™. https://www.mygenelog.com/variants/rs146962013
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