CYP19A1 · rs146939415
Where this position leads
Condition: Osteoarthritis
What the study found
Who was studied 37,589 British ancestry individuals.
The effect Each copy of the G allele shifted the measure 0.19 higher (95% confidence interval 0.13-0.25); p = 6 × 10−9.
How common The G allele had a frequency of about 99% in the people studied.
Where it sits Chromosome 15, band 15q21.2 — in an intron of MIR4713HG.
rs146939415 is a single position in the genome, in or near the CYP19A1 gene. Published research associates it with thigh bone marrow fat fraction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Journal of obesity 2025, PMID:40922984. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Thigh bone marrow fat fraction (rs146939415). MyGeneLog™. https://www.mygenelog.com/variants/rs146939415