FRMD5 · rs146906133
Where this position leads
What the study found
Who was studied 35,000 European ancestry cases, 33,478 European ancestry controls.
The effect Each copy of the T allele shifted the measure 0.38 higher (95% confidence interval 0.32-0.45); p = 2 × 10−8.
Where it sits Chromosome 15, band 15q15.3 — in an intron of FRMD5.
rs146906133 is a single position in the genome, in or near the FRMD5 gene. Published research associates it with urinary tract infection frequency. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Tonsillectomy (Throat Infection Susceptibility). The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Commun 2017, PMID:28928442. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.