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Epiretinal membrane

HSPA8 · rs146867887

What the study found

Who was studied 4,739 African American cases, 107,773 African American controls.

The effect Each copy of the A allele shifted the measure 0.919 higher (95% confidence interval 0.59-1.24); p = 3 × 10−8.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 11, band 11q24.1 — in an intron of HSPA8.

What each result means

A/A Two copies of the version the research linked to Epiretinal membrane. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Epiretinal membrane. That is a smaller link than two copies.
C/C No copy of the version the research linked to Epiretinal membrane. This is the starting point the study compared everyone against.
Source

Questions about rs146867887

What is rs146867887?

rs146867887 is a single position in the genome, in or near the HSPA8 gene. Published research associates it with epiretinal membrane. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs146867887 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146867887 come from?

GWAS Catalog, Cell genomics 2024, PMID:38870908. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Epiretinal membrane (rs146867887). MyGeneLog™. https://www.mygenelog.com/variants/rs146867887

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