Standard

Height (baseline)

MTCL2 · rs146841289

Where this position leads

Condition: Height

rs146841289 Condition: Height Height Condition rs146841289 rs146841289 MTCL2

What the study found

Who was studied 405,540 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0339 lower (95% confidence interval 0.023-0.044); p = 3 × 10−10.

How common The G allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 20, band 20q11.23 — in an intron of MTCL2.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Height (baseline) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Height (baseline).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Height (baseline) compared to the general population.
Source

Questions about rs146841289

What is rs146841289?

rs146841289 is a single position in the genome, in or near the MTCL2 gene. Published research associates it with height (baseline). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs146841289 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs146841289 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146841289 come from?

GWAS Catalog, Nature communications 2025, PMID:40374629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (baseline) (rs146841289). MyGeneLog™. https://www.mygenelog.com/variants/rs146841289

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