Sensitive

Systemic lupus erythematosus

near RPS10P13 · rs146761142

Where this position leads

Condition: Systemic Lupus Erythematosus

rs146761142 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs146761142 rs146761142 near RPS10P13

What the study found

Who was studied 1,639 East Asian ancestry cases, 2,410 East Asian ancestry controls.

The effect Each copy of the G allele shifted the measure 0.381 higher (95% confidence interval 0.25-0.51); p = 2 × 10−8.

Where it sits Chromosome 6, band 6p21.31 — between genes, 2.4 kb from RPS10P13.

What each result means

A/A No copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs146761142

What is rs146761142?

rs146761142 is a single position in the genome, in or near the near RPS10P13 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs146761142 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

Does having rs146761142 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146761142 come from?

GWAS Catalog, Molecular genetics and genomics : MGG 2021, PMID:34076728. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systemic lupus erythematosus (rs146761142). MyGeneLog™. https://www.mygenelog.com/variants/rs146761142

← See all variants