Standard

Medication use (agents acting on the renin-angiotensin system)

NGF-AS1 · rs146718647

What the study found

Who was studied 62,752 European ancestry cases, 174,778 European ancestry controls, 45,820 East Asian ancestry cases, 132,906 East Asian ancestry controls.

The effect Each copy of the T allele shifted the measure 0.19 higher (95% confidence interval 0.15-0.23); p = 7 × 10−17.

Where it sits Chromosome 1, band 1p13.2 — in an intron of NGF-AS1.

What each result means

C/C No copy of the version the research linked to Medication use (agents acting on the renin-angiotensin system). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Medication use (agents acting on the renin-angiotensin system). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Medication use (agents acting on the renin-angiotensin system). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs146718647

What is rs146718647?

rs146718647 is a single position in the genome, in or near the NGF-AS1 gene. Published research associates it with medication use (agents acting on the renin-angiotensin system). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs146718647 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146718647 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (agents acting on the renin-angiotensin system) (rs146718647). MyGeneLog™. https://www.mygenelog.com/variants/rs146718647

← See all variants