C/CPublished research associates this genotype with typical/baseline likelihood of Asthma — no copies of the reported risk allele. (GWAS Catalog, Eur Respir J 2019, PMID:31619474)
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Asthma. (GWAS Catalog, Eur Respir J 2019, PMID:31619474)
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Asthma compared to the general population. (GWAS Catalog, Eur Respir J 2019, PMID:31619474)
The European respiratory journal · 2019 · PMID 31619474
Questions about rs146597587
What is rs146597587?
rs146597587 is a single position in the genome, in or near the GLDC gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs146597587 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs146597587 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs146597587 come from?
GWAS Catalog, Eur Respir J 2019, PMID:31619474. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.