Sensitive

Prostate cancer

near MIR4686 · rs146569428

Where this position leads

Condition: Prostate Cancer

rs146569428 Condition: Prostate Cancer Prostate Cancer Condition rs146569428 rs146569428 near MIR4686

What the study found

Who was studied 7,822 European ancestry cases, 144,172 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.155 higher (95% confidence interval 0.12-0.2); p = 2 × 10−14.

Where it sits Chromosome 11, band 11p15.5 — between genes, 5.3 kb from MIR4686.

What each result means

A/A Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
Source

Questions about rs146569428

What is rs146569428?

rs146569428 is a single position in the genome, in or near the near MIR4686 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs146569428 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs146569428 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146569428 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs146569428). MyGeneLog™. https://www.mygenelog.com/variants/rs146569428

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