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Ubiquitin-conjugating enzyme E2 variant 2 levels

near GMNC · rs146550622

What the study found

Who was studied 2,721 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.19 higher (95% confidence interval 0.14-0.24); p = 3 × 10−11.

How common The C allele had a frequency of about 38% in the people studied.

Where it sits Chromosome 3, band 3q28 — between genes, 28.2 kb from GMNC.

What each result means

C/C Two copies of the version the research linked to Ubiquitin-conjugating enzyme E2 variant 2 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Ubiquitin-conjugating enzyme E2 variant 2 levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Ubiquitin-conjugating enzyme E2 variant 2 levels. This is the starting point the study compared everyone against.
Source

Questions about rs146550622

What is rs146550622?

rs146550622 is a single position in the genome, in or near the near GMNC gene. Published research associates it with ubiquitin-conjugating enzyme e2 variant 2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs146550622 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146550622 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Ubiquitin-conjugating enzyme E2 variant 2 levels (rs146550622). MyGeneLog™. https://www.mygenelog.com/variants/rs146550622

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