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Leukocyte telomere length

LRRIQ4 · rs146546514

What the study found

Who was studied 327,790 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.078 higher (95% confidence interval 0.058-0.098); p = 3 × 10−14.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 3, band 3q26.2 — in an intron of LRRIQ4.

What each result means

A/A Two copies of the version the research linked to Leukocyte telomere length. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Leukocyte telomere length. That is a smaller link than two copies.
C/C No copy of the version the research linked to Leukocyte telomere length. This is the starting point the study compared everyone against.
Source

Questions about rs146546514

What is rs146546514?

rs146546514 is a single position in the genome, in or near the LRRIQ4 gene. Published research associates it with leukocyte telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs146546514 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146546514 come from?

GWAS Catalog, GeroScience 2024, PMID:38837026. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Leukocyte telomere length (rs146546514). MyGeneLog™. https://www.mygenelog.com/variants/rs146546514

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