near HIP1R · rs146459385
Where this position leads
Condition: Childhood Body Mass Index
What the study found
Who was studied 342,566 European ancestry individuals.
The effect Each copy of the A allele shifted the measure 0.0424 lower (95% confidence interval 0.032-0.053); p = 9 × 10−15.
Where it sits Chromosome 12, band 12q24.31 — between genes, 0.5 kb from HIP1R.
rs146459385 is a single position in the genome, in or near the near HIP1R gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index (rs146459385). MyGeneLog™. https://www.mygenelog.com/variants/rs146459385