0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 405,540 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0267 higher (95% confidence interval 0.019-0.035); p = 4 × 10−11.
How common The G allele had a frequency of about 97% in the people studied.
Where it sits Chromosome 1, band 1q25.2 — in an intron of COP1.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Height (baseline) — no copies of the reported risk allele.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Height (baseline).
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Height (baseline) compared to the general population.
Nature communications · 2025 · PMID 40374629 · open access
Questions about rs146447727
What is rs146447727?
rs146447727 is a single position in the genome, in or near the COP1 gene. Published research associates it with height (baseline). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs146447727 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs146447727 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs146447727 come from?
GWAS Catalog, Nature communications 2025, PMID:40374629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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