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Who was studied 405,540 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0765 lower (95% confidence interval 0.068-0.085); p = 5 × 10−72.
How common The C allele had a frequency of about 98% in the people studied.
Where it sits Chromosome 3, band 3p21.2 — in an intron of DCAF1.
What each result means
C/CTwo copies of the version the research linked to Height (baseline). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Height (baseline). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Height (baseline). This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40374629 · open access
Questions about rs146370649
What is rs146370649?
rs146370649 is a single position in the genome, in or near the DCAF1 gene. Published research associates it with height (baseline). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs146370649 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs146370649 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs146370649 come from?
GWAS Catalog, Nature communications 2025, PMID:40374629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 2714123115Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others15Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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