Standard

Height

RAPGEF4 · rs146346995

Where this position leads

Condition: Height

rs146346995 Condition: Height Height Condition rs146346995 rs146346995 RAPGEF4

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0651 higher (95% confidence interval 0.046-0.084); p = 1 × 10−11.

Where it sits Chromosome 2, band 2q31.1 — in an intron of RAPGEF4.

What each result means

A/A Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Questions about rs146346995

What is rs146346995?

rs146346995 is a single position in the genome, in or near the RAPGEF4 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs146346995 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs146346995 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146346995 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs146346995). MyGeneLog™. https://www.mygenelog.com/variants/rs146346995

← See all variants