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Non-alcoholic chronic pancreatitis

JAKMIP2-AS1 · rs146303903

What the study found

Who was studied 584 European ancestry cases, 6,040 European ancestry controls.

The effect Each copy of the G allele carried 2.98 times the odds of Non-alcoholic chronic pancreatitis (95% confidence interval 2.10873513370054-4.21788937849748); p = 6 × 10−10.

How common The G allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 5, band 5q32 — in an intron of JAKMIP2-AS1.

What each result means

A/A No copy of the version the research linked to Non-alcoholic chronic pancreatitis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Non-alcoholic chronic pancreatitis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Non-alcoholic chronic pancreatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs146303903

What is rs146303903?

rs146303903 is a single position in the genome, in or near the JAKMIP2-AS1 gene. Published research associates it with non-alcoholic chronic pancreatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs146303903 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146303903 come from?

GWAS Catalog, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022, PMID:35331647. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Non-alcoholic chronic pancreatitis (rs146303903). MyGeneLog™. https://www.mygenelog.com/variants/rs146303903

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