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Total cholesterol levels

LINC01755 · rs146230035

What the study found

Who was studied 146,492 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.235 higher (95% confidence interval 0.19-0.28); p = 8 × 10−21.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 1, band 1p32.2 — in an intron of LINC01755.

What each result means

C/C No copy of the version the research linked to Total cholesterol levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Total cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Total cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs146230035

What is rs146230035?

rs146230035 is a single position in the genome, in or near the LINC01755 gene. Published research associates it with total cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs146230035 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146230035 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total cholesterol levels (rs146230035). MyGeneLog™. https://www.mygenelog.com/variants/rs146230035

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