Standard

Body mass index

SLC39A8 · rs146171187

Where this position leads

Condition: Childhood Body Mass Index

rs146171187 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs146171187 rs146171187 SLC39A8

What the study found

Who was studied 1,122,049 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.128 lower (95% confidence interval 0.094-0.162); p = 2 × 10−13.

Where it sits Chromosome 4, band 4q24 — in an intron of SLC39A8.

What each result means

A/A No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs146171187

What is rs146171187?

rs146171187 is a single position in the genome, in or near the SLC39A8 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs146171187 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs146171187 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146171187 come from?

GWAS Catalog, Nature communications 2022, PMID:36581621. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body mass index (rs146171187). MyGeneLog™. https://www.mygenelog.com/variants/rs146171187

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