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Energy expenditure

near HAPSTR1 · rs146169233

What the study found

Who was studied 5,461 European ancestry lean females, 2,726 European ancestry lean males, 6,563 European ancestry overweight or obese females, 4,020 European ancestry overweight or obese males..

The effect Each copy of the T allele shifted the measure 52 kcals higher (95% confidence interval 34-70); p = 2 × 10−8.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 16, band 16p13.2 — between genes, 27.1 kb from HAPSTR1.

What each result means

C/C No copy of the version the research linked to Energy expenditure. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Energy expenditure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Energy expenditure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs146169233

What is rs146169233?

rs146169233 is a single position in the genome, in or near the near HAPSTR1 gene. Published research associates it with energy expenditure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs146169233 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146169233 come from?

GWAS Catalog, PLoS One 2018, PMID:30071075. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Energy expenditure (rs146169233). MyGeneLog™. https://www.mygenelog.com/variants/rs146169233

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