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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 243,951 European and South Asian ancestry males.
The effect
Each copy of the T allele shifted the measure 0.0464 lower (95% confidence interval 0.04-0.053); p = 5 × 10−44.
How common The T allele had a frequency of about 10% in the people studied.
Where it sits Chromosome X, band Xq12 — between genes, 8.6 kb from EIF4BP9.
What each result means
A/ANo copy of the version the research linked to Testosterone levels. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Testosterone levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2025 · PMID 40229599 · open access
Questions about rs146116365
What is rs146116365?
rs146116365 is a single position in the genome, in or near the near EIF4BP9 gene. Published research associates it with testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs146116365 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs146116365 come from?
GWAS Catalog, Nature genetics 2025, PMID:40229599. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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