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Who was studied 29,739 Japanese ancestry cases, 240,675 Japanese ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.215 higher (95% confidence interval 0.14-0.29); p = 3 × 10−8.
How common The T allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 6, band 6q23.2 — in an intron of AKAP7.
What each result means
C/CNo copy of the version the research linked to Peptic ulcer disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Peptic ulcer disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Peptic ulcer disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2023 · PMID 38036781 · open access
Questions about rs146095444
What is rs146095444?
rs146095444 is a single position in the genome, in or near the AKAP7 gene. Published research associates it with peptic ulcer disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs146095444 linked to?
On MyGeneLog this position is linked to Peptic Ulcer Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs146095444 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs146095444 come from?
GWAS Catalog, Nature genetics 2023, PMID:38036781. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 826Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others6Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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