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Male-pattern baldness

TWIST2 · rs146095395

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs146095395 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs146095395 rs146095395 TWIST2

What the study found

Who was studied 52,874 British ancestry males.

The effect Each copy of the T allele shifted the measure 0.0607 higher; p = 7 × 10−12.

Where it sits Chromosome 2, band 2q37.3 — in an intron of TWIST2.

What each result means

C/C No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs146095395

What is rs146095395?

rs146095395 is a single position in the genome, in or near the TWIST2 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs146095395 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs146095395 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146095395 come from?

GWAS Catalog, PLoS Genet 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Male-pattern baldness (rs146095395). MyGeneLog™. https://www.mygenelog.com/variants/rs146095395

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