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Systemic infections

RSF1 · rs146072725

What the study found

Who was studied 26 Vis (founder/genetic isolate) cases, 36 Korculan (founder/genetic isolate) cases, 25 Split cases, 934 Vis (founder/genetic isolate) controls, 2,662 Korculan (founder/genetic isolate) controls, 941 Split controls.

The effect Each copy of the T allele carried 1.13 times the odds of Systemic infections (95% confidence interval 1.09-1.16); p = 8 × 10−13.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 11, band 11q14.1 — in an intron of RSF1.

What each result means

C/C No copy of the version the research linked to Systemic infections. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Systemic infections. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systemic infections. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs146072725

What is rs146072725?

rs146072725 is a single position in the genome, in or near the RSF1 gene. Published research associates it with systemic infections. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs146072725 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs146072725 come from?

GWAS Catalog, International journal of molecular sciences 2023, PMID:37108169. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systemic infections (rs146072725). MyGeneLog™. https://www.mygenelog.com/variants/rs146072725

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