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Acute pancreatitis (PheCode 577.1)

near SPINK1 · rs145959667

Where this position leads

Condition: Acute Pancreatitis

rs145959667 Condition: Acute Pancreatitis Acute Pancreatitis Condition rs145959667 rs145959667 near SPINK1

What the study found

Who was studied 3,143 African American or Afro-Caribbean cases, 117,167 African American or Afro-Caribbean controls, 7,613 European ancestry cases, 439,644 European ancestry controls, 1,099 Hispanic or Latin American cases, 58,206 Hispanic or Latin American controls.

The effect Each copy of the G allele shifted the measure 0.49 lower (95% confidence interval 0.42-0.56); p = 6 × 10−15.

How common The G allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 5, band 5q32 — between genes, 6.6 kb from SPINK1.

What each result means

A/A No copy of the version the research linked to Acute pancreatitis (PheCode 577.1). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Acute pancreatitis (PheCode 577.1). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Acute pancreatitis (PheCode 577.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs145959667

What is rs145959667?

rs145959667 is a single position in the genome, in or near the near SPINK1 gene. Published research associates it with acute pancreatitis (phecode 577.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs145959667 linked to?

On MyGeneLog this position is linked to Acute Pancreatitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs145959667 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs145959667 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Acute pancreatitis (PheCode 577.1) (rs145959667). MyGeneLog™. https://www.mygenelog.com/variants/rs145959667

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