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KLK7 protein levels

CD163L1 · rs145920606

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.172 higher (95% confidence interval 0.15-0.19); p = 1 × 10−72.

How common The G allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 12, band 12p13.31 — in an intron of CD163L1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of KLK7 protein levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with KLK7 protein levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of KLK7 protein levels compared to the general population.
Source

Questions about rs145920606

What is rs145920606?

rs145920606 is a single position in the genome, in or near the CD163L1 gene. Published research associates it with klk7 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs145920606 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs145920606 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

KLK7 protein levels (rs145920606). MyGeneLog™. https://www.mygenelog.com/variants/rs145920606

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