Standard

HDL cholesterol levels

SEMA3C · rs145837504

What the study found

Who was studied 58,701 Korean ancestry individuals.

The effect Each copy of the C allele shifted the measure 1.3 higher (95% confidence interval 0.99-1.61); p = 1 × 10−16.

Where it sits Chromosome 7, band 7q21.11 — in an intron of SEMA3C.

What each result means

C/C Two copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs145837504

What is rs145837504?

rs145837504 is a single position in the genome, in or near the SEMA3C gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs145837504 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs145837504 come from?

GWAS Catalog, Biomedicines 2022, PMID:35884923. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HDL cholesterol levels (rs145837504). MyGeneLog™. https://www.mygenelog.com/variants/rs145837504

← See all variants