SLCO1B3-SLCO1B7 · rs145816106
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,594 Chinese ancestry cases, 46,813 Chinese ancestry controls.
The effect Each copy of the A allele carried 1.41 times the odds of Isolated hypothyroxinemia in pregnancy (95% confidence interval 1.27-1.57); p = 4 × 10−10.
How common The A allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 12, band 12p12.2 — in an intron of SLCO1B3-SLCO1B7.
rs145816106 is a single position in the genome, in or near the SLCO1B3-SLCO1B7 gene. Published research associates it with isolated hypothyroxinemia in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2024, PMID:39266554. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Isolated hypothyroxinemia in pregnancy (rs145816106). MyGeneLog™. https://www.mygenelog.com/variants/rs145816106