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Who was studied 575,531 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0374 lower (95% confidence interval 0.033-0.042); p = 3 × 10−60.
Where it sits Chromosome 12, band 12q24.31 — in a non-coding transcript of CABP1-DT.
What each result means
C/CNo copy of the version the research linked to C-reactive protein levels (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to C-reactive protein levels (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to C-reactive protein levels (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 36376304 · open access
Questions about rs145738980
What is rs145738980?
rs145738980 is a single position in the genome, in or near the CABP1-DT gene. Published research associates it with c-reactive protein levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs145738980 linked to?
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs145738980 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs145738980 come from?
GWAS Catalog, Nature communications 2022, PMID:36376304. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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C-reactive protein levels (MTAG) (rs145738980). MyGeneLog™. https://www.mygenelog.com/variants/rs145738980