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Hip index

AKR1C2 · rs145611933

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 186,825 British ancestry men.

The effect Each copy of the C allele shifted the measure 0.0471 higher (95% confidence interval 0.032-0.062); p = 3 × 10⁻¹⁰.

Where it sits Chromosome 10, band 10p15.1 — between genes, 1.8 kb from AKR1C2.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hip index compared to the general population.

C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hip index.

G/G Published research associates this genotype with typical/baseline likelihood of Hip index — no copies of the reported risk allele.

Source

GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer

Christakoudi S, Evangelou E, Riboli E, Tsilidis KK

Scientific reports · 2021 · PMID 34021172 · open access

Questions about rs145611933

What is rs145611933?

rs145611933 is a single position in the genome, in or near the AKR1C2 gene. Published research associates it with hip index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs145611933 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs145611933 come from?

GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hip index (rs145611933). MyGeneLog™. https://www.mygenelog.com/variants/rs145611933

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