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Who was studied 12,502 Hispanic/Latino individuals; replicated in 4,772 Hispanic/Latino individuals.
The effect
Each copy of the C allele shifted the measure 0.39 pg higher (95% confidence interval 0.27-0.51); p = 3 × 10−12.
How common The C allele had a frequency of about 93% in the people studied.
Where it sits Chromosome 16, band 16p13.3 — between genes, 1.1 kb from HBAP1.
What each result means
C/CTwo copies of the version the research linked to Mean corpuscular hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Mean corpuscular hemoglobin. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Mean corpuscular hemoglobin. This is the starting point the study compared everyone against.
PLoS genetics · 2017 · PMID 28453575 · open access
Questions about rs145546625
What is rs145546625?
rs145546625 is a single position in the genome, in or near the HBA2 gene. Published research associates it with mean corpuscular hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs145546625 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs145546625 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs145546625 come from?
GWAS Catalog, PLoS Genet 2017, PMID:28453575. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 302211012318Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI10Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Mean corpuscular hemoglobin (rs145546625). MyGeneLog™. https://www.mygenelog.com/variants/rs145546625