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cAMP-specific 3,5-cyclic phosphodiesterase 4A levels

PDE4A · rs145530718

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 1.59 higher (95% confidence interval 1.5-1.69); p = 6 × 10−235.

How common The C allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 19, band 19p13.2 — in an intron of PDE4A.

What each result means

C/C Two copies of the version the research linked to cAMP-specific 3,5-cyclic phosphodiesterase 4A levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to cAMP-specific 3,5-cyclic phosphodiesterase 4A levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to cAMP-specific 3,5-cyclic phosphodiesterase 4A levels. This is the starting point the study compared everyone against.
Source

Questions about rs145530718

What is rs145530718?

rs145530718 is a single position in the genome, in or near the PDE4A gene. Published research associates it with camp-specific 3,5-cyclic phosphodiesterase 4a levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs145530718 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs145530718 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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cAMP-specific 3,5-cyclic phosphodiesterase 4A levels (rs145530718). MyGeneLog™. https://www.mygenelog.com/variants/rs145530718

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