A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Autism spectrum disorder or schizophrenia compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Autism spectrum disorder or schizophrenia.
G/GPublished research associates this genotype with typical/baseline likelihood of Autism spectrum disorder or schizophrenia — no copies of the reported risk allele.
Molecular autism · 2017 · PMID 28540026 · open access
Questions about rs145470632
What is rs145470632?
rs145470632 is a single position in the genome, in or near the HLA-DRB5 gene. Published research associates it with autism spectrum disorder or schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs145470632 linked to?
On MyGeneLog this position is linked to Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk). The research behind each link, and its sources, are set out on that condition page.
Does having rs145470632 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs145470632 come from?
GWAS Catalog, Mol Autism 2017, PMID:28540026. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.