Sensitive

Estimated glomerular filtration rate in sickle cell disease (Tractor method with African ancestry)

ARHGAP24 · rs145400585

What the study found

Who was studied up to 966 individuals.

The effect Each copy of the T allele shifted the measure 26.8 lower (95% confidence interval 17.38-36.27); p = 3 × 10−8.

Where it sits Chromosome 4, band 4q21.23 — in an intron of ARHGAP24.

What each result means

G/G No copy of the version the research linked to Estimated glomerular filtration rate in sickle cell disease (Tractor method with African ancestry). This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Estimated glomerular filtration rate in sickle cell disease (Tractor method with African ancestry). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Estimated glomerular filtration rate in sickle cell disease (Tractor method with African ancestry). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs145400585

What is rs145400585?

rs145400585 is a single position in the genome, in or near the ARHGAP24 gene. Published research associates it with estimated glomerular filtration rate in sickle cell disease (tractor method with african ancestry). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs145400585 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs145400585 come from?

GWAS Catalog, Blood advances 2026, PMID:42616615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Estimated glomerular filtration rate in sickle cell disease (Tractor method with African ancestry) (rs145400585). MyGeneLog™. https://www.mygenelog.com/variants/rs145400585

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