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Vertex-wise cortical thickness

near KCNK2 · rs1452628

What the study found

Who was studied 33,748 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 25.4 z score higher; p = 6 × 10−142.

How common The T allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 1, band 1q41 — between genes, 39.2 kb from KCNK2.

What each result means

A/A No copy of the version the research linked to Vertex-wise cortical thickness. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Vertex-wise cortical thickness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Vertex-wise cortical thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1452628

What is rs1452628?

rs1452628 is a single position in the genome, in or near the near KCNK2 gene. Published research associates it with vertex-wise cortical thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1452628 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1452628 come from?

GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vertex-wise cortical thickness (rs1452628). MyGeneLog™. https://www.mygenelog.com/variants/rs1452628

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