Sensitive

Early neurological instability after acute ischemic stroke

near COL11A1 · rs1451040

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 204 Hispanic individuals.

The effect Each copy of the T allele shifted the measure 4.13 lower; p = 3 × 10⁻⁸.

Where it sits Chromosome 1, band 1p21.1 — between genes, 183.3 kb from COL11A1.

What each result means

C/C No copy of the version the research linked to Early neurological instability after acute ischemic stroke. This is the starting point the study compared everyone against.

C/T One copy of the version the research linked to Early neurological instability after acute ischemic stroke. That is a smaller link than two copies.

T/T Two copies of the version the research linked to Early neurological instability after acute ischemic stroke. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke

Ibanez L, Heitsch L, Carrera C, Farias FHG, Del Aguila JL, Dhar R, Budde J, Bergmann K, Bradley J, Harari O, Phuah CL, Lemmens R

and 64 more — show all

Viana Oliveira Souza AA, Moniche F, Cabezas-Juan A, Arenillas JF, Krupinksi J, Cullell N, Torres-Aguila N, Muiño E, Cárcel-Márquez J, Marti-Fabregas J, Delgado-Mederos R, Marin-Bueno R, Hornick A, Vives-Bauza C, Navarro RD, Tur S, Jimenez C, Obach V, Segura T, Serrano-Heras G, Chung JW, Roquer J, Soriano-Tarraga C, Giralt-Steinhauer E, Mola-Caminal M, Pera J, Lapicka-Bodzioch K, Derbisz J, Davalos A, Lopez-Cancio E, Muñoz L, Tatlisumak T, Molina C, Ribo M, Bustamante A, Sobrino T, Castillo-Sanchez J, Campos F, Rodriguez-Castro E, Arias-Rivas S, Rodríguez-Yáñez M, Herbosa C, Ford AL, Gutierrez-Romero A, Uribe-Pacheco R, Arauz A, Lopes-Cendes I, Lowenkopf T, Barboza MA, Amini H, Stamova B, Ander BP, Sharp FR, Kim GM, Bang OY, Jimenez-Conde J, Slowik A, Stribian D, Tsai EA, Burkly LC, Montaner J, Fernandez-Cadenas I, Lee JM, Cruchaga C

Brain : a journal of neurology · 2022 · PMID 35213696

Questions about rs1451040

What is rs1451040?

rs1451040 is a single position in the genome, in or near the near COL11A1 gene. Published research associates it with early neurological instability after acute ischemic stroke. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1451040 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1451040 come from?

GWAS Catalog, Brain : a journal of neurology 2022, PMID:35213696. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Early neurological instability after acute ischemic stroke (rs1451040). MyGeneLog™. https://www.mygenelog.com/variants/rs1451040

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