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Who was studied 33,262 European ancestry cases, 804,234 European ancestry controls; replicated in 7,267 East Asian ancestry cases, 219,529 East Asian ancestry controls, 2,785 African American or Afro-Caribbean cases, 3,933 African American or Afro-Caribbean controls.
The effect
Each copy of the T allele shifted the measure 0.132 higher (95% confidence interval 0.1-0.16); p = 7 × 10−18.
Where it sits Chromosome 1, band 1q21.3 — between genes, 27.2 kb from CCDST.
What each result means
C/CNo copy of the version the research linked to Atopic dermatitis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Atopic dermatitis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Atopic dermatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of investigative dermatology · 2022 · PMID 35577104
Questions about rs144881827
What is rs144881827?
rs144881827 is a single position in the genome, in or near the near CCDST gene. Published research associates it with atopic dermatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs144881827 linked to?
On MyGeneLog this position is linked to Atopic Dermatitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs144881827 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs144881827 come from?
GWAS Catalog, The Journal of investigative dermatology 2022, PMID:35577104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 142210Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot2Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others10Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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