Standard

Proprotein convertase subtilisin/kexin type 7 levels

PAFAH1B2 · rs144600500

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.675 lower (95% confidence interval 0.48-0.87); p = 1 × 10−11.

How common The G allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 11, band 11q23.3 — in an intron of PAFAH1B2.

What each result means

A/A No copy of the version the research linked to Proprotein convertase subtilisin/kexin type 7 levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Proprotein convertase subtilisin/kexin type 7 levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Proprotein convertase subtilisin/kexin type 7 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs144600500

What is rs144600500?

rs144600500 is a single position in the genome, in or near the PAFAH1B2 gene. Published research associates it with proprotein convertase subtilisin/kexin type 7 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs144600500 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs144600500 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Proprotein convertase subtilisin/kexin type 7 levels (rs144600500). MyGeneLog™. https://www.mygenelog.com/variants/rs144600500

← See all variants