Standard

Aspartate aminotransferase (AST, minimum, inv-norm transformed)

near XCR1 · rs144564964

What the study found

Who was studied 112,345 African American or Afro-Caribbean individuals, 54,221 Hispanic or Latin American individuals, 5,834 East Asian ancestry individuals, 389,315 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.107 lower (95% confidence interval 0.081-0.133); p = 4 × 10−16.

How common The T allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 3, band 3p21.31 — between genes, 8.2 kb from XCR1.

What each result means

C/C No copy of the version the research linked to Aspartate aminotransferase (AST, minimum, inv-norm transformed). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Aspartate aminotransferase (AST, minimum, inv-norm transformed). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Aspartate aminotransferase (AST, minimum, inv-norm transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs144564964

What is rs144564964?

rs144564964 is a single position in the genome, in or near the near XCR1 gene. Published research associates it with aspartate aminotransferase (ast, minimum, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs144564964 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs144564964 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Aspartate aminotransferase (AST, minimum, inv-norm transformed) (rs144564964). MyGeneLog™. https://www.mygenelog.com/variants/rs144564964

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