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CD300LF protein levels

TTYH2 · rs144179857

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.146 lower (95% confidence interval 0.11-0.18); p = 3 × 10−20.

How common The G allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 17, band 17q25.1 — in an intron of TTYH2.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of CD300LF protein levels compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with CD300LF protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of CD300LF protein levels — no copies of the reported risk allele.
Source

Questions about rs144179857

What is rs144179857?

rs144179857 is a single position in the genome, in or near the TTYH2 gene. Published research associates it with cd300lf protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs144179857 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs144179857 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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CD300LF protein levels (rs144179857). MyGeneLog™. https://www.mygenelog.com/variants/rs144179857

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