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Ulcerative colitis (Tractor method with European ancestry)

CYP21A2 · rs144029176

Where this position leads

Condition: Ulcerative Colitis

rs144029176 Condition: Ulcerative Colitis Ulcerative Colitis Condition rs144029176 rs144029176 CYP21A2

What the study found

Who was studied up to 672 Hispanic cases, up to 5,042 Hispanic controls.

The effect Each copy of the T allele carried 5.32 times the odds of Ulcerative colitis (Tractor method with European ancestry) (95% confidence interval 3.132345658-9.029146679); p = 6 × 10−10.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — a missense change in CYP21A2.

What each result means

C/C No copy of the version the research linked to Ulcerative colitis (Tractor method with European ancestry). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Ulcerative colitis (Tractor method with European ancestry). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Ulcerative colitis (Tractor method with European ancestry). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs144029176

What is rs144029176?

rs144029176 is a single position in the genome, in or near the CYP21A2 gene. Published research associates it with ulcerative colitis (tractor method with european ancestry). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs144029176 linked to?

On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs144029176 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs144029176 come from?

GWAS Catalog, Gastroenterology 2026, PMID:41661118. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Ulcerative colitis (Tractor method with European ancestry) (rs144029176). MyGeneLog™. https://www.mygenelog.com/variants/rs144029176

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