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White blood cell count

near LINC02819 · rs143969748

What the study found

Who was studied 6,007 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals.

The effect Each copy of the A allele shifted the measure 0.35 lower (95% confidence interval 0.27-0.43); p = 1 × 10−19.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 1, band 1q23.2 — between genes, 1.2 kb from LINC02819.

What each result means

A/A Two copies of the version the research linked to White blood cell count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to White blood cell count. That is a smaller link than two copies.
G/G No copy of the version the research linked to White blood cell count. This is the starting point the study compared everyone against.
Source

Questions about rs143969748

What is rs143969748?

rs143969748 is a single position in the genome, in or near the near LINC02819 gene. Published research associates it with white blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs143969748 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs143969748 come from?

GWAS Catalog, Nature communications 2021, PMID:33623009. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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White blood cell count (rs143969748). MyGeneLog™. https://www.mygenelog.com/variants/rs143969748

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