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Total cholesterol levels (MTAG)

LINC01830 · rs1439200

What the study found

Who was studied 125,000 African ancestry individuals (MTAG boosted by high-density lipoprotein and triglyceride samples).

The effect Each copy of the G allele shifted the measure 0.023 lower (95% confidence interval 0.016-0.03); p = 7 × 10−11.

Where it sits Chromosome 2, band 2p24.1 — in an intron of LINC01830.

What each result means

A/A No copy of the version the research linked to Total cholesterol levels (MTAG). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Total cholesterol levels (MTAG). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Total cholesterol levels (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1439200

What is rs1439200?

rs1439200 is a single position in the genome, in or near the LINC01830 gene. Published research associates it with total cholesterol levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1439200 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1439200 come from?

GWAS Catalog, Nature communications 2023, PMID:37669986. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total cholesterol levels (MTAG) (rs1439200). MyGeneLog™. https://www.mygenelog.com/variants/rs1439200

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