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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 6861 European ancestry individuals; replicated in 4298 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.639 higher; p = 7 × 10−18.
How common The T allele had a frequency of about 98% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in a non-coding transcript of LINC02569.
What each result means
C/CNo copy of the version the research linked to Blood protein levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Blood protein levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Blood protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 30111768 · open access
Questions about rs143654430
What is rs143654430?
rs143654430 is a single position in the genome, in or near the LINC02569 gene. Published research associates it with blood protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs143654430 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs143654430 come from?
GWAS Catalog, Nature communications 2018, PMID:30111768. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Blood protein levels (rs143654430). MyGeneLog™. https://www.mygenelog.com/variants/rs143654430