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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 335 African American or Afro-Caribbean cases, 120,589 African American or Afro-Caribbean controls, 886 European ancestry cases, 447,693 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 4.23 lower (95% confidence interval 4.22-4.24); p = 4 × 10−11.
How common The A allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 1, band 1q32.2 — between genes, 66.1 kb from LINC01774.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Psychogenic disorder (PheCode 303.3) compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Psychogenic disorder (PheCode 303.3).
G/GPublished research associates this genotype with typical/baseline likelihood of Psychogenic disorder (PheCode 303.3) — no copies of the reported risk allele.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs143634281
What is rs143634281?
rs143634281 is a single position in the genome, in or near the near LINC01774 gene. Published research associates it with psychogenic disorder (phecode 303.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs143634281 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs143634281 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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