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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 337,196 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.022 lower (95% confidence interval 0.016-0.028); p = 1 × 10−11.
Where it sits Chromosome 15, band 15q25.2 — in an intron of SEC11A.
What each result means
A/ATwo copies of the version the research linked to Whole body fat mass (UKB data field 23100). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Whole body fat mass (UKB data field 23100). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Whole body fat mass (UKB data field 23100). This is the starting point the study compared everyone against.
Scientific reports · 2024 · PMID 38538606 · open access
Questions about rs143494045
What is rs143494045?
rs143494045 is a single position in the genome, in or near the SEC11A gene. Published research associates it with whole body fat mass (ukb data field 23100). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs143494045 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs143494045 come from?
GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Whole body fat mass (UKB data field 23100) (rs143494045). MyGeneLog™. https://www.mygenelog.com/variants/rs143494045