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Soluble transferrin receptor concentration

TMEM181 · rs143437464

What the study found

Who was studied 45,330 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.234 lower (95% confidence interval 0.16-0.31); p = 4 × 10−10.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 6, band 6q25.3 — in an intron of TMEM181.

What each result means

A/A Two copies of the version the research linked to Soluble transferrin receptor concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Soluble transferrin receptor concentration. That is a smaller link than two copies.
G/G No copy of the version the research linked to Soluble transferrin receptor concentration. This is the starting point the study compared everyone against.
Source

Questions about rs143437464

What is rs143437464?

rs143437464 is a single position in the genome, in or near the TMEM181 gene. Published research associates it with soluble transferrin receptor concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs143437464 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs143437464 come from?

GWAS Catalog, Communications biology 2024, PMID:39643614. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Soluble transferrin receptor concentration (rs143437464). MyGeneLog™. https://www.mygenelog.com/variants/rs143437464

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