Standard

Fasting plasma glucose

Y_RNA · rs143399767

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families..

The effect Each copy of the C allele shifted the measure 0.362 mmol/L higher (95% confidence interval 0.24-0.49); p = 1 × 10⁻⁸.

How common The C allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 9, band 9q22.31 — between genes, 2.5 kb from Y_RNA.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Fasting plasma glucose — no copies of the reported risk allele.

A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Fasting plasma glucose.

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Fasting plasma glucose compared to the general population.

Source

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

Nagy R, Boutin TS, Marten J, Huffman JE, Kerr SM, Campbell A, Evenden L, Gibson J, Amador C, Howard DM, Navarro P, Morris A

and 13 more — show all

Deary IJ, Hocking LJ, Padmanabhan S, Smith BH, Joshi P, Wilson JF, Hastie ND, Wright AF, McIntosh AM, Porteous DJ, Haley CS, Vitart V, Hayward C

Genome medicine · 2017 · PMID 28270201 · open access

Questions about rs143399767

What is rs143399767?

rs143399767 is a single position in the genome, in or near the Y_RNA gene. Published research associates it with fasting plasma glucose. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs143399767 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs143399767 come from?

GWAS Catalog, Genome Med 2017, PMID:28270201. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants