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Serum uric acid levels

SLC22A25 · rs143289410

What the study found

Who was studied 6,881 Korean ancestry individuals; replicated in 3,914 Korean ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.494 lower (95% confidence interval 0.35-0.63); p = 4 × 10−12.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 11, band 11q12.3 — in an intron of SLC22A10.

What each result means

A/A Two copies of the version the research linked to Serum uric acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Serum uric acid levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum uric acid levels. This is the starting point the study compared everyone against.
Source

Questions about rs143289410

What is rs143289410?

rs143289410 is a single position in the genome, in or near the SLC22A25 gene. Published research associates it with serum uric acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs143289410 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs143289410 come from?

GWAS Catalog, Scientific reports 2020, PMID:32514006. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum uric acid levels (rs143289410). MyGeneLog™. https://www.mygenelog.com/variants/rs143289410

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